They're missing their two best players / goalscorers. Andy Johnson (striker) won't be fit to play, and their other influential midfielder Tim Cahill is out for a while. They're a very tough and organised team. They'll most likely have a five man midfield and aim to defend for the majority of the match. I think United will win; better quality etc. However, if Ronaldo and Saha aren't playing for Man United, it might be worth placing a bet on Everton +1 or +1.5, if thats available.